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Biomedical Technology - Masters Degrees
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Markers of chronic immune activation and T-cell function in hyperglycaemia
(Cape Peninsula University of Technology, 2017)Type 2 diabetes mellitus (T2DM) is a chronic inflammatory condition characterised by hyperglycaemia; continuous activation of T-lymphocytes and immune dysregulation. Although the exact mechanisms of these phenomena are not ... -
DNA methylation : a risk factor for type 2 diabetes mellitus
(Cape Peninsula University of Technology, 2016)The early detection of individuals who are at risk of developing type 2 diabetes mellitus (T2DM) would decrease the morbidity and mortality associated with this disease. DNA methylation, the most widely studied epigenetic ... -
The role of Bcl-2 and bax protein expression on individual radiosensitivity
(Cape Peninsula University of Technology, 2017)Apoptosis is the dominant mechanism of cell death induced by radiation and is the key mechanism used to remove cells with significant DNA damage. Previous research investigated the feasibility of using the Leukocyte Apoptosis ... -
Validation of a recently proposed equation for the estimation of small, dense LDL particles from routine lipid measures in a population of mixed ancestry South Africans
(Cape Peninsula University of Technology, 2016)Cardiovascular diseases (CVD) are the leading cause of global mortality, of which over 75% occurred in low- and middle-income countries such as South Africa. The lipid profile, specifically decreased levels of high density ... -
An in vitro comparison of cellular destruction and metabolic effects occurring in stored, leuco-reduced and irradiated red blood cells
(Cape Peninsula University of Technology, 2016)Biochemical and haematological changes occur in red blood cellular products during the recommended storage period of 35 to 42 days at 1°C to 6°C. The restriction of the sodium/potassium pump at specified temperatures result ... -
Influence of temperature and pH on corrosion resistance of Ni–Cr and Co–Cr dental alloys on oral environment
(Cape Peninsula University of Technology, 2015)Dental alloys are widely used in direct contact with oral tissue. In recent years after the price of gold significantly increased, cheaper dental materials were generally considered in the market particularly dental ... -
DNA methylation : a risk factor for type 2 diabetes mellitus
(Cape Peninsula University of Technology, 2016)The early detection of individuals who are at risk of developing type 2 diabetes mellitus (T2DM) would decrease the morbidity and mortality associated with this disease. DNA methylation, the most widely studied epigenetic ... -
Synthesis of Co-Cr-Mo/ fluorapatie nano-composite coating by pulsed laser depositionfor dental applications
(Cape Peninsula University of Technology, 2016)Metallic materials play an essential role in assisting with the repair or replacement of bone tissue that has become diseased or damaged. Metals are more suitable for load bearing applications compared to ceramics or ... -
Platelet function and activation in mixed ancestry subjects with hyperglycemia, from the Western Cape, South Africa
(Cape Peninsula University of Technology, 2016)Type 2 diabetes mellitus (T2DM) is a metabolic disorder which is characterised by insulin resistance, defective insulin secretion or both. The chronic state of hyperglycemia in diabetes is associated with microvascular ... -
Effects of red palm oil-supplementation on oxidative stress biomarkers in an experimental rat model
(Cape Peninsula University of Technology, 2012)Oxidative stress, in recent times appears to be a major underlying risk factor in the occurrence of various diseases such as cardiovascular disease (CVD) and ischemic heart disease (IHD). During oxidative stress, there ... -
Antioxidant status of South African beverages and its role on the chemical parameters in human blood
(Cape Peninsula University of Technology, 2009)In recent years antioxidants present in various beverages have attracted a great deal of research interest due to their potential benefits to human health. Epidemiological evidence shows an indirect relationship between ... -
An epidemiological study in the greater Durban area of gram negative bacilli resistant to aminoglycoside antibiotics
(Cape Technikon, 1998)This study was undertaken to investigate resistance to aminoglycoside antibiotics and the transfer of resistance in selected Gram negative bacilli in hospitals in the Greater Durban area in order to determine whether the ... -
'n Ondersoek na die vir bepaling van serum- en toepassing van essaieringstelle verwysingswaardes vir vitamien rooiselfolaat by verskillende etniese groepe
(Cape Technikon, 1992)As early as 1822 it was discovered that treating a patient, who had a macrocytic anaemia, with a diet containing liver, a rich source of folic acid (folacin), brought about an excellent haematological response. extract, ... -
Tumour metabolism and radioprotection of normal tissue in Balb/c and CBA mice
(Cape Technikon, 1992)The steady state in a tumour rapidly changes with its growth and the subsequent deteriorating blood and nutrient supply. This adaptation in the steady state of the tumour is shown in the increased lactate dehydrogenase ... -
The effect of steroid hormones on the size of myometrial cells : a morphometric study
(Cape Technikon, 1997)The aims of this study were to measure: 1. Myometrial cells of menopausal uteri to establish whether they atrophy after the menopause. 2. Myometrial cells at different phases of the menstrual cycle to investigate ... -
Mitochondrial DNA heteroplasmy in radiation induced myelodysplasia and leukaemia
(Cape Technikon, 1996)Haematological defects observed in clonal deletions of mtDNA and the inhibition of mitochondrial function by benzene and chloramphenicol, suggest a role for mtDNA in the pathogenesis of radiation - induced preleukaemia ... -
A study to evaluate variable number of tandem repeat DNA polymorphisms in disputed paternity testing
(Cape Technikon, 1993)The use of genetic marker testing to resolve cases of disputed paternity, is well established. The number and range of systems used depends on the expertise of the laboratory, and for this reason various laboratories offer ... -
Genetic markers of rheumatoid arthritis in a Western Cape black and coloured population
(Cape Technikon, 1996)Intensive investigations in many different populations over the last decade, have indicated a failure to understand the inheritance of rheumatoid arthritis (RA). It was hoped that genes within the class II region of the ... -
The effect of Rooibos on trace elements absorption and biochemical parameters : a murine model
(Cape Peninsula University of Technology, 2014)Over the past few decades, it has been shown that various critical diseases including heart disease, cancer, and diabetes associated with free radical generation and low endogenous antioxidant capacity, lead to oxidative ... -
In vitro anti-bacterial activity of titanium oxide nano-composites containing benzalkonium chloride and chlorhexidine gluconate
(Cape Peninsula University of Technology, 2013)Newly developed and commercial dental resins which are commonly used nowadays have to be tested for their antimicrobial susceptibility. The purpose of this in vitro study was to investigate the antimicrobial activity of ...
