Loading...
Chemosensitivity of prostatic tumour cell lines under conditions of G2 block abrogation
Author(s)
Serafin, Antonio Mendes
Date Issued
2000
Type
Thesis
Publisher
Cape Technikon
Abstract
Cancer of the prostate gland is now recognised as one of the principal medical problems in males.
In the USA, cancer of the prostate is the second most commonly diagnosed cancer after skin cancer
and the second most common cause of death from cancer after lung cancer. In South Africa,
prostate cancer is the second most common cancer, with an estimated annual incidence of 19.1 per
LOO000 men (Sitas, 1994). However, this incidence is probably under-estimated, due to incomplete
records. Comparison of the incidence of prostate cancer in the different racial groups shows that it
is the second most common malignancy in the White, Black (African) and Mixed (Coloured) race
groups, and the fourth most common malignancy in Asian (Indian) men in South Africa.
Metastatic prostate cancer is refractory to hormone therapy and remains incurable. Hence, novel
therapeutic approaches are needed. These anticancer drugs can be tested in tumour cell lines, and
cell culture methods also permit testing of optimum conditions.
In the USA, cancer of the prostate is the second most commonly diagnosed cancer after skin cancer
and the second most common cause of death from cancer after lung cancer. In South Africa,
prostate cancer is the second most common cancer, with an estimated annual incidence of 19.1 per
LOO000 men (Sitas, 1994). However, this incidence is probably under-estimated, due to incomplete
records. Comparison of the incidence of prostate cancer in the different racial groups shows that it
is the second most common malignancy in the White, Black (African) and Mixed (Coloured) race
groups, and the fourth most common malignancy in Asian (Indian) men in South Africa.
Metastatic prostate cancer is refractory to hormone therapy and remains incurable. Hence, novel
therapeutic approaches are needed. These anticancer drugs can be tested in tumour cell lines, and
cell culture methods also permit testing of optimum conditions.
Additional information
Thesis (MTech (Biomedical Technology))--Cape Technikon, 2011.
File(s)![Thumbnail Image]()
Loading...
Name
2005566_Serafin_AM_Mtech_Bio_Tech_HWSci_2000_2005566.pdf
Description
Thesis
Size
20.86 MB
Format
Adobe PDF
Checksum
(MD5):eb656428eec2b62be39af8fc6e86bfa4